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protein ladder  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc protein ladder
    Protein Ladder, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 23 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/color+coded+prestained+protein+marker/pmc12868728-497-2-6?v=Cell+Signaling+Technology+Inc
    Average 94 stars, based on 23 article reviews
    protein ladder - by Bioz Stars, 2026-08
    94/100 stars

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    Image Search Results


    DIO-STZ hearts show alterations in key metabolic enzymes. (A) Myocardial bulk RNA-Seq analysis was performed in DIO-STZ and chow mice, as well as in both STZ and DIO mice. Principal component analysis as well as hierarchical cluster analysis of differentially regulated genes. (B) Ingenuity pathway analysis revealed that three of the four most strongly regulated canonical pathways in DIO-STZ hearts are related to lipid and fatty acid metabolism. (C) Summarized qPCR data for RNA expression of key metabolic enzymes Cpt1b , Cpt2 and Pdk4 (n=7-8). (D-E) Example western blots, and summarized data of CPT2, PLIN2, PLIN5, PDK4, BDH1, OXCT1/SCOT, and HMGCS2 protein levels (n=6 per group). Data are shown as means ± SD. Statistical analysis was performed using unpaired t-test. * P < 0.05, ** P < 0.01, *** P < 0.001, ns = not significant.

    Journal: bioRxiv

    Article Title: Obesity and diabetes related disturbances in systemic metabolism induce a cardiometabolic heart failure with preserved ejection fraction phenotype in a combined high-fat, high sucrose diet and streptozotocin mouse model

    doi: 10.1101/2025.10.23.684124

    Figure Lengend Snippet: DIO-STZ hearts show alterations in key metabolic enzymes. (A) Myocardial bulk RNA-Seq analysis was performed in DIO-STZ and chow mice, as well as in both STZ and DIO mice. Principal component analysis as well as hierarchical cluster analysis of differentially regulated genes. (B) Ingenuity pathway analysis revealed that three of the four most strongly regulated canonical pathways in DIO-STZ hearts are related to lipid and fatty acid metabolism. (C) Summarized qPCR data for RNA expression of key metabolic enzymes Cpt1b , Cpt2 and Pdk4 (n=7-8). (D-E) Example western blots, and summarized data of CPT2, PLIN2, PLIN5, PDK4, BDH1, OXCT1/SCOT, and HMGCS2 protein levels (n=6 per group). Data are shown as means ± SD. Statistical analysis was performed using unpaired t-test. * P < 0.05, ** P < 0.01, *** P < 0.001, ns = not significant.

    Article Snippet: Membranes were blocked with Odyssey blocking buffer (LI-COR Biosciences) and probed with antibodies against BDH1 (15417-1-AP), PDK4 (12949-1-AP), OXCT1/SCOT (12175-1-AP), all from Proteintech, CPT2 (PA5-19222, Thermo Fisher), PLIN2 (ab52356, Abcam), PLIN5 (GP31, Progen), and HMGCS2 (#20940, Cell Signaling).

    Techniques: RNA Sequencing, RNA Expression, Western Blot